ME/CFS Research Summaries

Tag: 🧪-Biomarker✕

94 items with this tag.

Dec 22, 2025
Machine Learning Analysis of Post-Acute COVID Symptoms Identifies Distinct Clusters, Severity Groups, and Trajectories
- 🧪-Biomarker
- ⭐-Landmark
Dec 19, 2025
Genetic Insights into Circulating Complement Proteins in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Potential Inflammatory Subgroup
- 🧪-Biomarker
Dec 16, 2025
Mapping the complexity of ME/CFS: Evidence for abnormal energy metabolism, altered immune profile, and vascular dysfunction.
- 🧪-Biomarker
- ⭐-Landmark
Dec 15, 2025
Inefficient energy consumption is related to post exertional malaise during cardiopulmonary exercise testing in long COVID
- 🧪-Biomarker
Dec 12, 2025
Alterations in gut microbiota and associated metabolites in patients with chronic fatigue syndrome
- 🧪-Biomarker
Dec 12, 2025
Long COVID involves activation of proinflammatory and immune exhaustion pathways
- ⭐-Landmark
- 🧪-Biomarker
Dec 10, 2025
Abnormal T-Cell activation and cytotoxic T-Cell frequency discriminate symptom severity in myalgic encephalomyelitis/chronic fatigue syndrome.
- 🧪-Biomarker
Dec 10, 2025
Exaggerated IFN-I Response in Long COVID PBMCs Following Exposure to Viral Mimics
- 🧪-Biomarker
Dec 10, 2025
Large-scale investigation confirms TRPM3 ion channel dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- 🧪-Biomarker
- ⭐-Landmark
Dec 10, 2025
£1.1m awarded to investigate links between ME/CFS and Long Covid
Dec 09, 2025
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): diagnosis and management.
- 🧪-Biomarker
- 💊-Treatment
Dec 08, 2025
Comparable Immune Alterations and Inflammatory Signatures in ME/CFS and Long COVID
- 🧪-Biomarker
- ⭐-Landmark
Dec 05, 2025
Persistent Attenuation of Lymphocyte Subsets After Mass SARS-CoV-2 Infection
- 🧪-Biomarker
- ⭐-Landmark
Dec 04, 2025
The lingering shadow of epidemics: post-acute sequelae across history.
- 🧪-Biomarker
- ⭐-Landmark
Dec 03, 2025
Identification of Novel Reproducible Combinatorial Genetic Risk Factors for Myalgic Encephalomyelitis in the DecodeME Patient Cohort and Commonalities with Long COVID
- 🧪-Biomarker
- ⭐-Landmark
Dec 03, 2025
Immune transcriptomic changes in Australian Gulf War veterans
- 🧪-Biomarker
Dec 02, 2025
Peripheral Levels of Selected Biomarkers in Patients with Post-Sarcoidosis Chronic Fatigue Syndrome
- 🧪-Biomarker
Dec 02, 2025
Risk Factors for Severe Post-COVID Condition in Children, Adolescents, and Young Adults
- 🧪-Biomarker
- ⭐-Landmark
Dec 01, 2025
Managing chronic fatigue conditions with overlapping symptoms, and the health policies and social services supporting those affected
- 🧪-Biomarker
- 💊-Treatment
Dec 01, 2025
Microstructural White Matter Impairments in Chronic Fatigue Syndrome: Evidence of Segmental Injury in the Cingulum Bundle
Nov 28, 2025
Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK Biobank
- 🧪-Biomarker
- ⭐-Landmark
Nov 27, 2025
Glymphatic System Dysregulation as a Key Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- 🧪-Biomarker
Nov 26, 2025
SARS-CoV-2 Spike Protein Amyloid Fibrils Impair Fibrin Formation and Fibrinolysis
- ⭐-Landmark
- 🧪-Biomarker
Nov 25, 2025
Altered brain tissue microstructure and neurochemical profiles in long COVID and recovered COVID-19 individuals: A multimodal MRI study
- 🧪-Biomarker
Nov 20, 2025
Mucosal Viruses in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Missing Piece of the Puzzle?
- 🧪-Biomarker
Nov 20, 2025
Pathogenic IgG from long COVID patients with neurological sequelae triggers sensitive but not cognitive impairments upon transfer into mice
- 🧪-Biomarker
Nov 20, 2025
Single cell epigenomic profiling identifies a distinct classical monocyte subset driving inflammation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME)
- 🧪-Biomarker
Nov 18, 2025
Integrated immune, hormonal, and transcriptomic profiling reveals sex-specific dysregulation in long COVID patients with ME/CFS
- 🧪-Biomarker
- ⭐-Landmark
Nov 15, 2025
Temporal dynamics of the plasma proteomic landscape reveals maladaptation in ME/CFS following exertion
- 🧪-Biomarker
- ⭐-Landmark
Nov 07, 2025
Research Into ME/CFS Pathology Points to Possible Treatments
Nov 07, 2025
SARS-CoV-2 spike protein causes synaptic dysfunction and p-tau and α-synuclein aggregation leading cognitive impairment: The protective role of metformin
- 💊-Treatment
- 🧪-Biomarker
Nov 07, 2025
The Clinical Relevance of Mast Cell Activation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- 🧪-Biomarker
- 💊-Treatment
Nov 07, 2025
The Role of Nuclear and Mitochondrial DNA in Myalgic Encephalomyelitis: Molecular Insights into Susceptibility and Dysfunction
- 🧪-Biomarker
- 💊-Treatment
Oct 31, 2025
Hyperbaric oxygen therapy improves clinical symptoms and functional capacity and restores thalamic connectivity in ME/CFS
- 🧪-Biomarker
- 💊-Treatment
Oct 30, 2025
Leveraging Explainable Automated Machine Learning (AutoML) and Metabolomics for Robust Diagnosis and Pathophysiological Insights in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
- 🧪-Biomarker
Oct 24, 2025
HLA and pathogens in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and other post-infection conditions
- 🧪-Biomarker
- ⭐-Landmark
Oct 21, 2025
Low-dose rapamycin alleviates clinical symptoms of fatigue and PEM in ME/CFS patients via improvement of autophagy: a pilot study
Oct 17, 2025
Urinary Peptidomic Profiling in Post-Acute Sequelae of SARS-CoV-2 Infection: A Case-Control Study
- 🧪-Biomarker
Oct 14, 2025
Autonomic phenotyping, brain blood flow control, and cognitive-motor-integration in Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome: A pilot study.
- 🧪-Biomarker
Oct 13, 2025
Soluble IL-2R: A potential therapeutic target for mitochondrial dysfunction in post-COVID fatigue syndrome
- 🧪-Biomarker
- 💊-Treatment
Oct 08, 2025
Development and validation of blood-based diagnostic biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using EpiSwitch® 3-dimensional genomic regulatory immuno-genetic profiling
- 🧪-Biomarker
- ⭐-Landmark
Oct 01, 2025
Severe COVID-19 induces prolonged elevation of the acute-phase protein pentraxin 3
- 🧪-Biomarker
Oct 01, 2025
Systemic increase of AMPA receptors associated with cognitive impairment of long COVID
- 🧪-Biomarker
- ⭐-Landmark
Sep 29, 2025
Better understanding complex pathomechanisms in central nervous system disorders as a prerequisite for improved diagnostic and therapeutic approaches.
- 🧪-Biomarker
- 💊-Treatment
Sep 26, 2025
The Potential Causes Of Myasthenia And Fasciculations In The Severely Ill Me/Cfs-Patient: Role Of Disturbed Electrophysiology
- 🧪-Biomarker
Sep 26, 2025
The gut microbial composition is different in chronic fatigue syndrome than in healthy controls
- 🧪-Biomarker
Sep 23, 2025
Evidence of clinical and brain recovery in post-COVID-19 condition: a three-year follow-up study
- 🧪-Biomarker
Sep 19, 2025
Exploratory study on autoantibodies to arginine-rich human peptides mimicking Epstein-Barr virus in women with post-COVID and myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
Sep 17, 2025
Gulf War Illness, Fibromyalgia, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID Overlap in Common Symptoms and Underlying Biological Mechanisms: Implications for Future Therapeutic Strategies
- 🧪-Biomarker
- 💊-Treatment
Sep 12, 2025
Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in Myalgic Encephalomyelitis
- 🧪-Biomarker
Sep 09, 2025
Anti-neuronal and anti-mitochondrial autoantibodies are associated with lower functional status and more severe respiratory symptoms in post COVID syndrome
- 🧪-Biomarker
Sep 09, 2025
Feasibility and tolerability of dual-target repetitive transcranial magnetic stimulation (rTMS) for treatment of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): An open label pilot study
- 🧪-Biomarker
- 💊-Treatment
Sep 08, 2025
The NLRP3 inflammasome as a key pathway in the affective and chronic fatigue symptoms of Long COVID
- 🧪-Biomarker
Sep 05, 2025
Autonomic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Findings from the Multi-Site Clinical Assessment of ME/CFS (MCAM) Study in the USA
- 🧪-Biomarker
Sep 03, 2025
Heightened innate immunity may trigger chronic inflammation, fatigue and post-exertional malaise in ME/CFS
- 🧪-Biomarker
- ⭐-Landmark
Sep 03, 2025
Precision Medicine Study of Post-Exertional Malaise Epigenetic Changes in Myalgic Encephalomyelitis/Chronic Fatigue Patients During Exercise
- 🧪-Biomarker
Aug 31, 2025
Killer cell immunoglobulin-like receptor (KIR) alleles suggested to be associated with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
- 🧪-Biomarker
Aug 29, 2025
Advancing research on regulatory autoantibodies targeting GPCRs: Insights from the 5th international symposium
- 🧪-Biomarker
- 📰-News
Aug 29, 2025
The emerging role of exosomal LncRNAs in chronic fatigue syndrome: from intercellular communication to disease biomarkers
- 🧪-Biomarker
Aug 28, 2025
Haptoglobin phenotypes and structural variants associate with post-exertional malaise and cognitive dysfunction in myalgic encephalomyelitis
- 🧪-Biomarker
- ⭐-Landmark
Aug 26, 2025
Mapping cerebral blood flow in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and orthostatic intolerance: insights from a systematic review
- 🧪-Biomarker
- ⭐-Landmark
Aug 11, 2025
Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
- ⭐-Landmark
Aug 11, 2025
Microfluidic assessment of PO2-regulated RBC capillary velocity in ME/CFS
Aug 10, 2025
ME/CFS and PASC Patient-Derived Immunoglobulin Complexes Disrupt Mitochondrial Function and Alter Inflammatory Marker Secretion
- 🧪-Biomarker
- ⭐-Landmark
Aug 08, 2025
Circulating FGF-21 as a Disease-Modifying Factor Associated with Distinct Symptoms and Cognitive Profiles in Myalgic Encephalomyelitis and Fibromyalgia
- 🧪-Biomarker
Aug 06, 2025
Genetic depletion of early autophagy protein ATG13 impairs mitochondrial energy metabolism, augments oxidative stress, induces the polarization of macrophages to M1 inflammatory mode, and compromises myelin integrity in skeletal muscle
- 🧪-Biomarker
Aug 06, 2025
Initial findings from the DecodeME genome-wide association study of myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
- ⭐-Landmark
Jul 28, 2025
Biomarkers over Time: From Visual Contrast Sensitivity to Transcriptomics in Differentiating Chronic Inflammatory Response Syndrome and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- 🧪-Biomarker
- 💊-Treatment
Jul 25, 2025
AI-driven multi-omics modeling of myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
- ⭐-Landmark
Jul 15, 2025
Two neurocognitive domains identified for patients with myalgic encephalomyelitis/chronic fatigue syndrome and post-acute sequelae of COVID-19
- 🧪-Biomarker
Jul 09, 2025
Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome-a clinical pilot study
Jul 07, 2025
SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis
May 29, 2025
How pandemics reshape our brain: Common links and targets between long-haul COVID-19, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), oxidative stress, and neurodegeneration.
- 🧪-Biomarker
May 19, 2025
Low-Dose naltrexone restored TRPM3 ion channel function in natural killer cells from long COVID patients
May 16, 2025
The sensitising effect of IgG in fibromyalgia syndrome is mediated by Mrgprb2 in mast cells
- ⭐-Landmark
- 🧪-Biomarker
Apr 15, 2025
Autoantibody targeting therapies in post COVID syndrome and myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
- 💊-Treatment
Apr 01, 2025
Microvascular Dysfunction and Basal Membrane Thickening in Skeletal Muscle in ME/CFS and Post-COVID
- 🧪-Biomarker
- ⭐-Landmark
Feb 19, 2025
Tragus Nerve Stimulation Attenuates Postural Orthostatic Tachycardia Syndrome in Post COVID-19 Infection
- 🧪-Biomarker
- 💊-Treatment
Dec 26, 2024
A novel frameshift mutation in ADCK1 identified in a case of chronic fatigue syndrome successfully treated with oral 5-ALA/SFC
- 🧪-Biomarker
- 💊-Treatment
Nov 06, 2024
Key Pathophysiological Role of Skeletal Muscle Disturbance in Post COVID and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Accumulated Evidence
Sep 06, 2024
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome
- 🧪-Biomarker
- 💊-Treatment
Apr 08, 2024
Longitudinal cytokine and multi-modal health data of an extremely severe ME/CFS patient with HSD reveals insights into immunopathology, and disease severity
Feb 21, 2024
Chronic fatigue syndrome linked to widespread energy, immune and vascular changes
- 🧪-Biomarker
- ⭐-Landmark
Dec 27, 2023
Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series
- 🧪-Biomarker
- 💊-Treatment
Nov 15, 2023
Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome
- 🧪-Biomarker
Oct 09, 2023
Observational Study of Repeat Immunoadsorption (RIA) in Post-COVID ME/CFS Patients with Elevated ß2-Adrenergic Receptor Autoantibodies—An Interim Report
- 🧪-Biomarker
- 💊-Treatment
May 26, 2023
Long Covid Patients Successfully Treated by Means of Heparin-Mediated Extracorporeal LDL Precipitation (H.E.L.P.) Apheresis
- 🧪-Biomarker
- 💊-Treatment
Dec 09, 2022
Muscle sodium content in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- 🧪-Biomarker
May 15, 2022
Acute Effect of Pyridostigmine in Exertional Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Randomized Placebo-Controlled Clinical Trial
May 09, 2022
The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure
- 🧪-Biomarker
- 💊-Treatment
Mar 31, 2022
Plasma metabolomics reveals disrupted response and recovery following maximal exercise in myalgic encephalomyelitis/ chronic fatigue syndrome
- 🧪-Biomarker
Feb 06, 2020
An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients
- 🧪-Biomarker
Jul 04, 2019
Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases
- 🧪-Biomarker
Feb 10, 2015
Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness
- 🧪-Biomarker
- ⭐-Landmark

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